Case 11: Postural Tachycardia Syndrome with Positive Antibodies Against the P/Q-type of Calcium Channel

Orthostatic symptoms in postural tachycardia syndrome (POTS) (shortness of breath, lightheadedness, fatigue, and others) are due cerebral hypoperfusion associated with reduced cerebral blood flow velocity (CBFv), which is induced by hyperventilation. Immunomodulatory therapy using immune globulins may be effective in small fiber neuropathy with a positive antibody against the P/Q-type calcium channel.