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ChemInform Abstract: ANTICOCCIDIAL ACTIVITY OF CROWN POLYETHERS

Authors :
George R. Brown
Alan J. Foubister
Source :
Chemischer Informationsdienst. 14
Publication Year :
1983
Publisher :
Wiley, 1983.

Abstract

Anticoccidial activity in vitro against Eimeria tenella is reported for crown polyethers with ring sizes from 14 to 30 atoms. The most potent compounds, 4 and 9, were found active at 0.33 ppm, but none were active in vivo. Test results are discussed in terms of lipophilic shielding of complexed cations.

Subjects

Subjects :
biology
Chemistry
In vivo
parasitic diseases
Crown (botany)
General Medicine
Ring (chemistry)
biology.organism_classification
Medicinal chemistry
Eimeria

Details

ISSN :
00092975
Volume :
14
Database :
OpenAIRE
Journal :
Chemischer Informationsdienst
Accession number :
edsair.doi...........e8a467a215acbd5408042693e2d789f0
Full Text :
https://doi.org/10.1002/chin.198334230
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