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Misfolded superoxide dismutase-1 in CSF from amyotrophic lateral sclerosis patients

Authors :
Stefan L. Marklund
Peter M. Andersen
Per Zetterström
Thomas Brännström
Source :
Journal of Neurochemistry. 117:91-99
Publication Year :
2011
Publisher :
Wiley, 2011.

Abstract

Several of the superoxide dismutase-1 (SOD1) mutations linked to amyotrophic lateral sclerosis (ALS) lead to synthesis of structurally defective molecules, suggesting that any cytotoxic conformatio ...

Details

ISSN :
00223042
Volume :
117
Database :
OpenAIRE
Journal :
Journal of Neurochemistry
Accession number :
edsair.doi...........e74394c4343e9efd7c7a26ca9129a693
Full Text :
https://doi.org/10.1111/j.1471-4159.2011.07177.x