ChemInform Abstract: Asymmetric Synthesis of (3S,1′S)-3-(1-Amino-2,2,2-trifluoroethyl)-1-(alkyl)-indolin-2-one Derivatives by Addition of (S)-N-t-Butylsulfinyl-3,3,3-trifluoroacetaldimine to 1-(Alkyl)-indolin-2-ones

Enolates of indolin-2-ones react cleanly with the chiral imine (II) to afford adducts (III) and (V) in good diastereoselectivity.