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The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis

Authors :
Dirk Trauner
Sherry R. Chemler
Samuel J. Danishefsky
Source :
Angewandte Chemie International Edition. 40:4544-4568
Publication Year :
2001
Publisher :
Wiley, 2001.

Abstract

The development of new reactions that facilitate the creative and efficient synthesis of molecular structures with desirable properties continues to fascinate chemists. The test of a significant contribution is its acceptance over time by the scientific community. The B-alkyl Suzuki-Miyaura cross-coupling reaction appears to be one such reaction. Since its disclosure by Suzuki and Miyaura in 1986, this reaction has been an attractive solution to challenging synthetic problems.

Details

ISSN :
14337851
Volume :
40
Database :
OpenAIRE
Journal :
Angewandte Chemie International Edition
Accession number :
edsair.doi...........e561503e48458f51faa1e65f206bc29d
Full Text :
https://doi.org/10.1002/1521-3773(20011217)40:24<4544::aid-anie4544>3.0.co;2-n