ChemInform Abstract: Cholinesterases: Structure of the Active Site and Mechanism of the Effect of Cholinergic Receptor Blockers on the Rate of Interaction with Ligands

Modern views on the structure of cholinesterase active sites and the mechanism of their interaction with organophosphorus inhibitors are considered. The attention is focused on the mechanism of the effect of cholinergic receptor blockers, acetylcholine antagonists, on the rate of interaction of acetylcholine esterase with organophosphorus inhibitors.