S852 IN VIVO SELECTION FOR CORRECTED BETA-GLOBIN ALLELES AFTER CRISPR/CAS9 EDITING IN HUMAN SICKLE HEMATOPOIETIC STEM CELLS ENHANCES THERAPEUTIC POTENTIAL

Authors :: J.T. Vu
Dario Boffelli
M. DeWitt
Wendy Magis
M. Walters
Zulema Romero
Donald B. Kohn
David I. K. Martin
S. Wyman
J.E. Corn
B. Campo Fernandez
Source :: HemaSphere. 3:380
Publication Year :: 2019
Publisher :: Ovid Technologies (Wolters Kluwer Health), 2019.

Subjects :: Genetics
Haematopoiesis
In vivo
CRISPR
Beta globin
Hematology
Stem cell
Allele
Biology
Selection (genetic algorithm)

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