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Cardioprotection, attenuated systemic inflammation, and survival benefit of β1-adrenoceptor blockade in severe sepsis in rats*
- Source :
- Critical Care Medicine. 38:388-394
- Publication Year :
- 2010
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2010.
-
Abstract
- Objective:To explore the hypothesis that beta-1 adrenoreceptor blockade may be protective through the attenuation of sympathetic hyperactivity and catecholaminergic inflammatory effects on cardiac and hepatic function.Design:Prospective, randomized, controlled study.Setting:Animal laboratory in a un
Details
- ISSN :
- 00903493
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Critical Care Medicine
- Accession number :
- edsair.doi...........e4fd72230b0447fa2a1d455646927de4
- Full Text :
- https://doi.org/10.1097/ccm.0b013e3181c03dfa