Back to Search Start Over

Primary lymphomas of the central nervous system. Questions of epidemiology and treatment. Clinical example of multidisciplinary approach in therapy

Authors :
N. E. Voinov
A. U. Ulitin
T. V. Chitanava
S. S. Sklyar
A. V. Petrov
Source :
Translational Medicine. 9:49-59
Publication Year :
2022
Publisher :
Arterialnaya Gipertenziya, 2022.

Abstract

Background. Currently, the frequency of occurrence of neoplasms is emerging in the world. Under conditions of a general tumor, brain tumors are rare (0.7–1.5 %). However, high mortality, disability, limited life expectancy of patients, high economic and social inferiority, raise concerns about the medical organization of care, development and social adaptation. Of particular importance among the causes of primary brain tumors is the congenital or acquired growth of immunodeficiency. The growth in the number of drug addicts led to the elimination of the annual epidemic at the end of the 70s and the increase in the number of patients with immunodeficiency syndrome (AIDS), due to which the growth of a brain tumor began to develop in this population group. The number of Russian patients with lymphoma is also steadily increasing.Objective. Consider an illustrative clinical case that reflects the expected continuity in patients with ordinary CNS lymphoma.Design and methods. A 50-year-old patient with moderate memory loss was examined using various methods: MRI, PET-CT and etc.Results. Based on histological and immunohistochemical studies, diffuse large B-cell lymphoma of the CNS was diagnosed. There was a positive trend in the reduction of tumor size after radiation therapy.Conclusion. Primary CNS lymphoma is becoming an active epidemiological problem of society, requiring comprehensive multidisciplinary monitoring. Only high vigilance in terms of lymphoma and well-coordinated work of multidisciplinary specialists can help to perform the correct diagnostics and patient management.

Details

ISSN :
24105155 and 23114495
Volume :
9
Database :
OpenAIRE
Journal :
Translational Medicine
Accession number :
edsair.doi...........e4e714b0d6f4f290caef35d4bd8fe60d
Full Text :
https://doi.org/10.18705/2311-4495-2022-9-1-49-59