Preparation of Furfuryl-fish gelatin (F-f.gel) cured using visible-light and its application as an anti-adhesion agent

Adhesions occurring on a variety tissues and operation sites are a serious side effect of surgery and may require additional surgery for removal. Therefore, Furfuryl-fish gelatin (F-f.gel) was synthesized by introducing a furan ring to fish gelatin for application as an anti-adhesion agent. F-f.gel was cured by visible-light irradiation, which changed the material from a solution to a film. The prepared F-f.gel was characterized by proton nuclear mag- netic resonance spectroscopy ( 1 H NMR), substitution ratio, gel permeation chromatography (GPC), methyl thiazolyl tetrazolium (MTT) assay, and tests for measuring photo immobilization, water contact angle (WCA), and cell attach- ment. The results showed that F-f.gel was effective as an anti-adhesion agent.