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Nutrition in children with exocrine pancreatic insufficiency

Authors :
Yuhua Zheng
Shikib Mostamand
Source :
Frontiers in Pediatrics. 11
Publication Year :
2023
Publisher :
Frontiers Media SA, 2023.

Abstract

Exocrine pancreatic insufficiency (EPI) is a condition defined as pancreatic loss of exocrine function, including decreased digestive enzymes and bicarbonate secretion, which leads to maldigestion and malabsorption of nutrients. It is a common complication in many pancreatic disorders. If left undiagnosed, EPI can cause poor digestion of food, chronic diarrhea, severe malnutrition and related complications. Nutritional status and fat-soluble vitamins should be carefully assessed and monitored in patients with EPI. Early diagnosis of EPI is clinically important for appropriate nutritional support and initiating pancreatic enzyme replacement therapy (PERT) which could significantly improve patient outcomes. The evaluation of nutritional status and related unique management in children with EPI will be discussed in this review.

Details

ISSN :
22962360
Volume :
11
Database :
OpenAIRE
Journal :
Frontiers in Pediatrics
Accession number :
edsair.doi...........e3516ce5654fbbdbe961d8d417e1e0fd