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Convenient Synthesis of VolatileStreptomycesLactones

Authors :
Perunninakulath S. Parameswaran
Santosh G. Tilve
Chandan P. Amonkar
Source :
Synthesis. :2341-2344
Publication Year :
2005
Publisher :
Georg Thieme Verlag KG, 2005.

Abstract

A convenient three-step synthetic approach towards 3-alkyl-5-methyl-2[5H]furanones is described. The steps involved in the synthesis are domino primary alcohol oxidation-Wittig reaction, acid-catalysed lactonisation and isomerisation. This synthetic approach has been exploited to synthesise four Streptomyces lactones.

Details

ISSN :
1437210X and 00397881
Database :
OpenAIRE
Journal :
Synthesis
Accession number :
edsair.doi...........e30b9fc0c847bdbede7c765d4543be66
Full Text :
https://doi.org/10.1055/s-2005-870025