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EFFECT OF SACUBITRIL/VALSARTAN ON BIOMARKERS OF MYOCARDIAL STRESS IN PATIENTS HOSPITALIZED WITH ACUTE HEART FAILURE IN PIONEER-HF

Authors :
Eugene Braunwald
Kevin McCague
Carol I. Duffy
Ricardo Rocha
David A. Morrow
Margaret F. Prescott
Eric J. Velazquez
Adam D. DeVore
Source :
Journal of the American College of Cardiology. 73:682
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Circulating high-sensitivity cardiac troponin (hsTn) and soluble ST2 (sST2) reflect myocardial stress in pts w/ heart failure (HF). In contrast, production of cGMP in response to activation of natriuretic peptide receptors has favorable effects on cardiac afterload and preload. The effects of

Details

ISSN :
07351097
Volume :
73
Database :
OpenAIRE
Journal :
Journal of the American College of Cardiology
Accession number :
edsair.doi...........e2f296a7149e822878d59ecd0bbcadb7
Full Text :
https://doi.org/10.1016/s0735-1097(19)31290-2