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Ureteral segment replacement using an ovine fetal urachus duct (new xenogenic graft) in dogs
- Source :
- Comparative Clinical Pathology. 18:125-129
- Publication Year :
- 2008
- Publisher :
- Springer Science and Business Media LLC, 2008.
-
Abstract
- The ureter is an important part of the urinary system that can be affected by several disorders such as congenital malformations, extensive iatrogenic ureteral obstruction, ureteritis, retroperitoneal fibrosis, trauma, necrosis, calculi, tumors, etc. We wished to determine whether ovine fetal urachus duct will be accepted when used as a ureteral replacement material in other species. The ureters of five adult native dogs were approached through a ventral midline laparotomy incision. A segment of 3-cm midureter was resected unilaterally. The left ureteral segments were replaced with ovine fetal urachus duct using 5-0 PDS interrupted sutures. Internal ureteral catheter was left for 6 weeks. The patency of the ureters was assessed by intravenous pyelography at 2 and 8 weeks after the surgery, while inflammation and regeneration were assessed grossly and histologically. All five urachus transplantations were accepted successfully in radiological, macroscopical, and histological evaluation. The ovine fetal urachus seems to be an embryonic tissue of extremely low antigenicity and therefore suitable for transplantation.
- Subjects :
- medicine.medical_specialty
business.industry
medicine.medical_treatment
Urinary system
Ureteritis
urologic and male genital diseases
Retroperitoneal fibrosis
medicine.disease
female genital diseases and pregnancy complications
Pathology and Forensic Medicine
Surgery
Transplantation
medicine.anatomical_structure
Ureter
Laparotomy
medicine
Anatomy
medicine.symptom
business
Duct (anatomy)
Urachus
Subjects
Details
- ISSN :
- 1618565X and 16185641
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Comparative Clinical Pathology
- Accession number :
- edsair.doi...........e2a6a8b794e39e688b155e7c18c03647