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Evaluation of a model-based attenuation correction method on whole-body 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging
- Source :
- Radiological Physics and Technology. 14:70-81
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- The bone cannot be evaluated using magnetic resonance attenuation correction (MRAC) with the Dixon sequence. To solve this issue, the present study aimed to evaluate model-based AC for whole-body 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/magnetic resonance imaging (MRI) by creating bone segmentation. We analyzed and evaluated the data of 31 consecutive patients. The Biograph mMR (Siemens Healthcare) was used for clinical whole-body 18F-FDG PET/MRI with the conventional MRAC method, and OSIRIX MD software was used to analyze the images. After the examination, the new model-based post-processing MRAC was applied to create μ-maps with bone segmentation, and retrospective PET reconstruction was performed using this μ-map. The bone structures of all patients created using model-based MRAC were visually evaluated. Standard uptake values (SUVs) at 11 anatomical positions in PET images, corrected using the μ-map with and without bone segmentation, were measured and compared. The model-based post-processing MRAC was run for all patients, without errors. Visual evaluation revealed that the model-based post-processing MRAC exhibited poor results for six patients. Furthermore, it exhibited an increasing trend of SUV in the brain compared to the conventional method. Locations other than the brain indicated a similar or decreasing trend. The two methods showed a good linear correlation for all patients. However, patients aged
- Subjects :
- Positron emission tomography–magnetic resonance imaging
Radiation
Materials science
medicine.diagnostic_test
business.industry
medicine.medical_treatment
Physical Therapy, Sports Therapy and Rehabilitation
Magnetic resonance imaging
General Medicine
030218 nuclear medicine & medical imaging
Radiation therapy
Fluorodeoxyglucose positron emission tomography
03 medical and health sciences
0302 clinical medicine
Positron emission tomography
030220 oncology & carcinogenesis
medicine
Radiology, Nuclear Medicine and imaging
Nuclear medicine
business
Whole body
Correction for attenuation
Bone segmentation
Subjects
Details
- ISSN :
- 18650341 and 18650333
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Radiological Physics and Technology
- Accession number :
- edsair.doi...........e1ab699d330f7df48477fbf3c8c5ee48