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Focal lymphocytic infiltration in aging human palatal salivary glands: a comparative study with labial salivary glands

Focal lymphocytic infiltration in aging human palatal salivary glands: a comparative study with labial salivary glands

Authors :
Yehuda Hiss
Amos Buchner
Dan Dayan
Marilena Vered
Elena Haimovici
Source :
Journal of Oral Pathology & Medicine. 30:7-11
Publication Year :
2001
Publisher :
Wiley, 2001.

Abstract

Investigation of age-related prevalence of various types of focal lymphocytic infiltration (FLI) and degrees of histomorphologic changes was conducted on 120 biopsies of palatal and labial salivary glands (PSG and LSG, respectively) obtained from autopsy subjects free of salivary gland tumors/diseases. Biopsies were divided into young ( 60 years, n=45) age groups. A modified Chisholm & Mason grading system was used to record grades of FLI and a modified Greenspan et al. system was used to evaluate the severity of histomorphologic changes. The prevalence of FLI in PSG increased significantly from 10% in the young group to 46.6% in the old group (P=0.0012). No significant changes were found with aging in LSG. FLI was significantly more prevalent in the adult and old age groups in PSG as compared with LSG (P=0.015 and P=0.003, respectively). Both glands demonstrated significant histomorphologic changes among age groups (p

Details

ISSN :
09042512
Volume :
30
Database :
OpenAIRE
Journal :
Journal of Oral Pathology & Medicine
Accession number :
edsair.doi...........defc413fb0fb2ec3de55d10297e4aa19
Full Text :
https://doi.org/10.1034/j.1600-0714.2001.300102.x