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Focal lymphocytic infiltration in aging human palatal salivary glands: a comparative study with labial salivary glands
Focal lymphocytic infiltration in aging human palatal salivary glands: a comparative study with labial salivary glands
- Source :
- Journal of Oral Pathology & Medicine. 30:7-11
- Publication Year :
- 2001
- Publisher :
- Wiley, 2001.
-
Abstract
- Investigation of age-related prevalence of various types of focal lymphocytic infiltration (FLI) and degrees of histomorphologic changes was conducted on 120 biopsies of palatal and labial salivary glands (PSG and LSG, respectively) obtained from autopsy subjects free of salivary gland tumors/diseases. Biopsies were divided into young ( 60 years, n=45) age groups. A modified Chisholm & Mason grading system was used to record grades of FLI and a modified Greenspan et al. system was used to evaluate the severity of histomorphologic changes. The prevalence of FLI in PSG increased significantly from 10% in the young group to 46.6% in the old group (P=0.0012). No significant changes were found with aging in LSG. FLI was significantly more prevalent in the adult and old age groups in PSG as compared with LSG (P=0.015 and P=0.003, respectively). Both glands demonstrated significant histomorphologic changes among age groups (p
- Subjects :
- Cancer Research
Pathology
medicine.medical_specialty
Lymphocytic infiltration
medicine.diagnostic_test
Salivary gland
business.industry
Lymphocyte
fungi
Autopsy
Pathology and Forensic Medicine
medicine.anatomical_structure
Otorhinolaryngology
Immunopathology
Biopsy
medicine
Periodontics
Histopathology
sense organs
Oral Surgery
Young adult
skin and connective tissue diseases
business
Subjects
Details
- ISSN :
- 09042512
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Journal of Oral Pathology & Medicine
- Accession number :
- edsair.doi...........defc413fb0fb2ec3de55d10297e4aa19
- Full Text :
- https://doi.org/10.1034/j.1600-0714.2001.300102.x