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Cell-based therapies for Parkinson's disease

Cell-based therapies for Parkinson's disease

Authors :
George A. Foster
B.M.J. Stringer
Source :
Drug Discovery Today: Therapeutic Strategies. 1:43-49
Publication Year :
2004
Publisher :
Elsevier BV, 2004.

Abstract

A restorative therapy for a disease such as Parkinson's, where substantial cellular degeneration has already occurred at the time of diagnosis, is likely to require a more complex intervention than simply enhancing dopamine output in the brain. Here we assess the value and feasibility of a variety of strategies aimed at either replacing the lost neuronal circuitry or providing one-off delivery of corrective and/or neuroprotective genes.

Details

ISSN :
17406773
Volume :
1
Database :
OpenAIRE
Journal :
Drug Discovery Today: Therapeutic Strategies
Accession number :
edsair.doi...........de367907f8253c1cc50496afe0b5f612
Full Text :
https://doi.org/10.1016/j.ddstr.2004.08.004