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Cell-based therapies for Parkinson's disease
Cell-based therapies for Parkinson's disease
- Source :
- Drug Discovery Today: Therapeutic Strategies. 1:43-49
- Publication Year :
- 2004
- Publisher :
- Elsevier BV, 2004.
-
Abstract
- A restorative therapy for a disease such as Parkinson's, where substantial cellular degeneration has already occurred at the time of diagnosis, is likely to require a more complex intervention than simply enhancing dopamine output in the brain. Here we assess the value and feasibility of a variety of strategies aimed at either replacing the lost neuronal circuitry or providing one-off delivery of corrective and/or neuroprotective genes.
- Subjects :
- Pharmacology
medicine.medical_specialty
Parkinson's disease
business.industry
Disease
medicine.disease
Neuronal circuitry
Neuroprotection
Dopamine
Intervention (counseling)
Drug Discovery
Physical therapy
Molecular Medicine
Medicine
business
Cellular degeneration
Neuroscience
Cell based
medicine.drug
Subjects
Details
- ISSN :
- 17406773
- Volume :
- 1
- Database :
- OpenAIRE
- Journal :
- Drug Discovery Today: Therapeutic Strategies
- Accession number :
- edsair.doi...........de367907f8253c1cc50496afe0b5f612
- Full Text :
- https://doi.org/10.1016/j.ddstr.2004.08.004