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Synthesis of regioisomeric N- and O-alkylated 3-polyfluoroalkyl-1,2-dihydroquinoxalin-2-ones
- Source :
- Russian Chemical Bulletin. 60:937-941
- Publication Year :
- 2011
- Publisher :
- Springer Science and Business Media LLC, 2011.
-
Abstract
- 3-Polyfluoroalkyl-1,2-dihydroquinoxalin-2-ones react with 4-bromobutyl acetate to furnish 1-(4-acetoxybutyl)quinoxalin-2-ones and 2-(4-acetoxybutoxy)quinoxalines in the ratio 2: 1. Deacylation of these compounds under acidic conditions gives the corresponding 1-(4-hydroxybutyl)- and 2-(4-hydroxybutoxy)-substituted quinoxalines. The structures of compounds synthesized were established by X-ray crystallography, IR spectroscopy, 1H and 19F NMR spectroscopy, GLC-MS.
Details
- ISSN :
- 15739171 and 10665285
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Russian Chemical Bulletin
- Accession number :
- edsair.doi...........ddb3362b2eedef1250e4019c7176951d