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Phosphinic acid inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme a reductase
- Source :
- Bioorganic & Medicinal Chemistry Letters. 1:151-154
- Publication Year :
- 1991
- Publisher :
- Elsevier BV, 1991.
-
Abstract
- Compound 3 was designed as a prototype for a new class of phosphorus-based inhibitors of 3-hydorxy-3-methylglutaryl-coenzyme A reductase. The synthesis and biochemical evaluation of compound 3 are described.
Details
- ISSN :
- 0960894X
- Volume :
- 1
- Database :
- OpenAIRE
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Accession number :
- edsair.doi...........dc613d911f88cfce2e1bbf610feaf0e4