Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor

Authors :: Sutton Scott Channing
Daniel W. Widlicka
Christopher B. Morris
Holly Strohmeyer
Cheryl Myers Hayward
Sebastien Monfette
Lindsay D. Nicholson
Jean-Nicolas Desrosiers
Michael Paul Burns
Jeremy Steflik
Eric C. Hansen
Michele T. Buetti-Weekly
Paul Bowles
Rajesh Kumar
Lu Han
Ian Hotham
Kris N. Jones
Shengquan Duan
Source :: Organic Process Research & Development. 26:879-890
Publication Year :: 2021
Publisher :: American Chemical Society (ACS), 2021.

Subjects :: biology
Cyclin-dependent kinase
Chemistry
Organic Chemistry
Key (cryptography)
biology.protein
Physical and Theoretical Chemistry
Reductive amination
Combinatorial chemistry

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