Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation

Authors :: Scott C. Rosenberg
Frances Shanahan
Sayumi Yamazoe
Marc Kschonsak
Yi J. Zeng
James Lee
Emile Plise
Ivana Yen
Christopher M. Rose
John G. Quinn
Lewis J. Gazzard
Benjamin T. Walters
Donald S. Kirkpatrick
Steven T. Staben
Scott A. Foster
Shiva Malek
Source :: Cell Chemical Biology. 30:175-187.e15
Publication Year :: 2023
Publisher :: Elsevier BV, 2023.

Subjects :: Pharmacology
Clinical Biochemistry
Drug Discovery
Molecular Medicine
Molecular Biology
Biochemistry

Tools