Some Important Factors in Cadaver-Donor Kidney Transplantation

The results of 88 cadaver-donor renal first transplants from the Newcastle Transplantation Centre have been reviewed after a minimum period of 6 months post transplant. They show the significant benefit of two antigen identity at the second HL-A locus between kidney donor and recipient. Pretransplant blood transfusion showed a beneficial effect on kidney survival. Cases with preformed cytotoxic antibodies showed a favourable outcome compared to cases without antibody, provided the crossmatch was negative. Rh(D) positive recipients showed a significant association with satisfactory outcome when compared to the Rh(D) negative recipients.