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TIM4+ adipose tissue-resident macrophages: new modulators of adiposity
- Source :
- Nature Reviews Endocrinology. 17:645-646
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Adipose tissue macrophages (ATMs) have important roles in the regulation of inflammatory responses and insulin resistance in obesity. A new study reports that a subpopulation of ATMs, TIM4+ resident ATMs, modulate adipocyte size via platelet-derived growth factor-CC production during development and diet-induced adipose tissue expansion.
Details
- ISSN :
- 17595037 and 17595029
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Nature Reviews Endocrinology
- Accession number :
- edsair.doi...........d9d41e9e0e303feffd98b27252fb95d6