Research on the Effectiveness and Safety of Bronchial Thermoplasty in Patients with Chronic Obstructive Pulmonary Disease

Objective To investigate the clinical efficacy and safety of bronchial thermoplasty (BT) in treating chronic obstructive pulmonary disease (COPD) patients. Methods Clinical data of 57 COPD patients were randomized into control (n = 29, conventional inhalation drug) or observation group (n = 28, convention inhalation drug plus BT). Primary outcomes were differences in clinical symptom changes, pulmonary function-related indicators, 6-min walk test (6MWT), COPD assessment test (CAT) score, Modified Medical Research Council (mMRC) and acute exacerbation incidence from baseline to average of 3 and 12 months. Safety was assessed by adverse events. Results FVC, FEV1 and FEV1% predicted value in both groups improved to varying degrees post-treatment compared with those pre-treatment (P