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Left Atrial Strain in the Repaired Tetralogy of Fallot Population: Comparisons to Biventricular Function, Native T1 Values, Exercise Parameters and Healthy Controls
- Source :
- Pediatric Cardiology. 42:1102-1110
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Non-invasive imaging markers in patients with repaired tetralogy of Fallot (rTOF) are still being investigated to inform clinical decision making. Atrial function is a prognostic indicator in many acquired and congenital heart diseases. We sought to examine the relationship between cardiac MRI (CMR)-derived indices of left atrial (LA) function, native left ventricular (LV) T1 values, biventricular systolic function, and exercise capacity in rTOF. Sixty-six patients with rTOF without prior pulmonary valve replacement who underwent CMR (median age 18.5 years) were identified. Twenty-one adult rTOF patients (age range 19–32 years) were compared with 20 age-matched healthy volunteers (age range 19–34 years). LA reservoir, conduit, and pump global longitudinal strain (GLS) and strain rate (SR) were determined by tissue tracking. Native LV T1 values were measured on rTOF patients. Pearson correlations were performed to determine bivariate associations. Adult rTOF patients had higher pump GLS, pump:conduit, and pump:reservoir GLS ratios, and lower conduit:reservoir GLS ratio, LV ejection fraction (EF), and right ventricular EF compared to controls (p
- Subjects :
- medicine.medical_specialty
Population
030204 cardiovascular system & hematology
Left atrial strain
03 medical and health sciences
0302 clinical medicine
Cardiac magnetic resonance imaging
Internal medicine
medicine
Diastolic function
cardiovascular diseases
Young adult
education
Tetralogy of Fallot
education.field_of_study
Ejection fraction
medicine.diagnostic_test
business.industry
medicine.disease
Cardiac surgery
030228 respiratory system
Pediatrics, Perinatology and Child Health
cardiovascular system
Cardiology
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 14321971 and 01720643
- Volume :
- 42
- Database :
- OpenAIRE
- Journal :
- Pediatric Cardiology
- Accession number :
- edsair.doi...........d93bb1aaa6a3c4b733cad3e076f156bc
- Full Text :
- https://doi.org/10.1007/s00246-021-02587-0