Additional file 3: Figure S2. of Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study

TTR knockdown with patisiran in patients taking a tetramer stabilizer. (a) Baseline TTR levels by stabilizer use (all cohorts). (b) TTR knockdown by patisiran (0.3Â mg/kg cohorts; error bars represent SEM). SEM: standard error of the mean; TTR: transthyretin. (DOCX 260 kb)