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Novel Lipoprotein Markers Remain Elevated Despite Statin Therapy After Heart Transplant

Authors :
M.T. Hassanein
Richard H. Cooke
Melissa C. Smallfield
Maureen Flattery
Sanah Christopher
Keyur B. Shah
Source :
The Journal of Heart and Lung Transplantation. 33:S284-S285
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

s S285 < 50% were excluded. Transmitral flow velocity variables were utilized (peak velocity during early (E) and late (A) filling, medial and lateral annular diastolic velocities (e medial, e lateral). Estimated PCWP was calculated using the following formula (ePCWP = 1.24 * (E /e lateral) + 1.9) whereas invasive PCWP (iPCWP) was calculated using pulmonary artery catheter. Results: In our cohort (age, median 56 years (45-63), 57 male (80%), mean EF (63 ± 7%), mean iPCWP was 12 ± 4 mmHg and mean ePCWP was 13 ± 3 mmHg. Strong correlation was noted between iPCWP and E (r= 0.5, P= < 0.0001), E/e lateral (r= 0.53, P= < 0.0001), but weak correlation with E/e medial (r= 0.34, P= 0.002). Using linear regression analysis, a strong significant correlation existed between iPCWP and ePCWP (r= 0.53, P= < 0.0001). Conclusion: In heart transplant recipients, ePCWP correlates with iPCWP, and E/e lateral was the strongest among diastolic echocardiographic indices.

Details

ISSN :
10532498
Volume :
33
Database :
OpenAIRE
Journal :
The Journal of Heart and Lung Transplantation
Accession number :
edsair.doi...........d8ff9cfffc02c8110dba9ad5d3b35f75
Full Text :
https://doi.org/10.1016/j.healun.2014.01.759