Oral manifestations of Sjögren's syndrome

Sjogren's syndrome is a chronic autoimmune disease complex characterized by inflammation of the exocrine glands, primarily resulting in keratoconjunctivitis sicca, hyposalivation and xerostomia, or dry mouth. Dry mouth is one of the most easily recognized components and may lead the clinician to diagnosis. Hyposalivation is more than an inconvenience, having a significant adverse effect on health and quality of life. Early recognition of this condition may minimize some of the adverse sequelae. A dental evaluation in patients with confirmed or suspected Sjogren's is recommended. The focus of this review article is to highlight oral manifestations of Sjogren's syndrome to include pathogenesis, clinical presentation, implications for health, diagnostic tools, management strategies and future perspectives.