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Synthesis and transformations of dihydroxy-2H-1-benzopyran-2-ones

Authors :
Dmitry N. Kuznetsov
A. N. Fakhrutdinov
S. S. Bobylev
K. I. Kobrakov
A. G. Ruchkina
Source :
Russian Journal of Organic Chemistry. 51:1572-1577
Publication Year :
2015
Publisher :
Pleiades Publishing Ltd, 2015.

Abstract

Proceeding from 2,4,6-trihydroxytoluene (methylphloroglucinol) dihydroxy-2H-1-benzopyran-2-ones were prepared, and also their bromo and acyl derivatives. The structure of compounds synthesized was established, and their potential pharmacokinetic properties were estimated by means of computer simulation.

Details

ISSN :
16083393 and 10704280
Volume :
51
Database :
OpenAIRE
Journal :
Russian Journal of Organic Chemistry
Accession number :
edsair.doi...........d7bd0afa2f69510e24f40472b60895ce
Full Text :
https://doi.org/10.1134/s1070428015110093