Nonimmune Haemolytic Disorders (RBC Membrane Abnormalities)

This chapter presents six cases. The final diagnosis includes hereditary spherocytosis, hereditary elliptocytosis, hereditary stomatocytosis, Melanesian ovalocytosis, hereditary pyropoikilocytosis, and paroxysmal nocturnal haemoglobinuria. The pathophysiology of each condition is explained and the tests listed that confirm the diagnosis. There are blood film images of the diagnostic morphology for each case and these include spherocytosis, elliptocytosis, stomatocyte, target cell, poikilocytosis, and polychromasia.