23-letnia chora na astmę oskrzelową z utrwalonymi zaburzeniami wentylacji ciężkiego stopnia

A 23-year-old female reported with atopic asthma and allergic rhinitis diagnosed in childhood, and complaints of frequent exacerbations since adolescence. Spirometry showed gradual progression of obstruction – at the age of 20 – representing very severe obturation. The patient never smoked and had no exposition to any potential irritation factors. Due to frequent exacerbations, the patient often required systemic glucocorticoids; at the age of 21, she was diagnosed with TB. After the antituberculosis treatment was completed, reversibility test was negative, and slow progression of obstruction was still observed (FEV1 20% of predicted value). The patient had presented depression symptoms. She was qualified for anti-IgE treatment; after 8 months, clinically significant improvement was observed – the number of exacerbations was reduced and systemic GCS has been stopped. Spirometry had showed improvement with FEV1 – 38% of predicted. As the exercise tolerance improved, the patient has resumed her academic studies.