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Management of locally recurrent rectal cancer
- Source :
- Seminars in Colon and Rectal Surgery. 30:85-88
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- The diagnosis and management of recurrent rectal cancer is surgically and oncologically challenging. Recurrence usually presents within 1–3 years of treatment for primary tumor, and diagnostic workup should assess pelvic resectability and workup for metastatic disease. Treatment includes neoadjuvant chemotherapy and/or radiotherapy, as well as surgical resection when an R0 resection is feasible. Neoadjuvant chemotherapy and radiotherapy is recommended in chemo/radiotherapy naive patients. Preoperative or intraoperative reirradiation is feasible, but the long term impact on likelihood of R0 resection and survivability is controversial. Chemoradiation may also be used to palliate unresectable disease.
- Subjects :
- medicine.medical_specialty
Chemotherapy
business.industry
medicine.medical_treatment
Gastroenterology
Unresectable disease
Disease
medicine.disease
Primary tumor
Therapy naive
Radiation therapy
03 medical and health sciences
0302 clinical medicine
030220 oncology & carcinogenesis
medicine
030211 gastroenterology & hepatology
Surgery
Radiology
business
R0 resection
Recurrent Rectal Cancer
Subjects
Details
- ISSN :
- 10431489
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Seminars in Colon and Rectal Surgery
- Accession number :
- edsair.doi...........d6c73c3e7d784002337e5baebc79a7b8