Role of vasoactive drugs in the OAB complex treatment

Aim of the study.To investigate the vasoactive drugs for urinary bladder wall ischemia correction, based on its role in OAB pathogenesis. Patients and methods.OAB treatment in 150 women was performed. In addition to the standard anticholinergic therapy microcirculation corrector was prescribed to some patients with insufficient treatment efficacy. Results.The combination of simultaneous prescription of anticholinergic and vasoactive drugs was effective for OAB treatment. The treatment resulted in significant decrease of the OAB symptoms. Conclusion.Low efficacy of M-cholinolytic therapy of the OAB patients is determined by the blood flow disturbances in the urinary bladder wall. It is reasonable to include the vasoactive drugs in complex OAB therapy.