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Micropatterns Based on Deformation of a Viscoelastic Honeycomb Mesh
- Source :
- Langmuir. 19:6193-6201
- Publication Year :
- 2003
- Publisher :
- American Chemical Society (ACS), 2003.
-
Abstract
- We report that various geometric patterns can be formed upon mechanical deformation of hexagonal micro polymer mesh. The patterning of micromesh can be applied to the fabrication of micropatterned soft-materials for cell culturing. A microporous film was prepared from a viscoelastic polymer, poly(e-caprolactone). The film was a hexagonal mesh of 4 μm diameter. Plastic deformation of the film was caused by loading tensile force in one direction. Geometrical patterns such as elongated hexagons, rectangles, squares, and triangles were found in the stretched microporous film. These four types of deformation were reproduced by computer simulations using a viscoelastic network of hexagonally connected viscoelastic bonds. On the stretched hexagonal mesh, cardiac myocytes formed fibrous tissue where cells were aligned along the direction of the long axis of micropores. The hierarchical structure of blood vessels could be modeled by the coculture of endothelial cells and smooth muscle cells using a stretched honey...
- Subjects :
- chemistry.chemical_classification
Fabrication
Materials science
genetic structures
Surfaces and Interfaces
Fibrous tissue
Polymer
Microporous material
Condensed Matter Physics
Viscoelasticity
chemistry
Smooth muscle
Electrochemistry
Honeycomb
General Materials Science
Deformation (engineering)
Composite material
Spectroscopy
Subjects
Details
- ISSN :
- 15205827 and 07437463
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Langmuir
- Accession number :
- edsair.doi...........d555845d27d9db974ecdc5a18ff83154