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Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism
- Publisher :
- Massachusetts Medical Society MMS
-
Abstract
- Background The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyroxine provided clinical benefits in older persons with this condition. Methods We conducted a double-blind, randomized, placebo-controlled, parallel-group trial involving 737 adults who were at least 65 years of age and who had persisting subclinical hypothyroidism (thyrotropin level, 4.60 to 19.99 mIU per liter; free thyroxine level within the reference range). A total of 368 patients were assigned to receive levothyroxine (at a starting dose of 50 μg daily, or 25 μg if the body weight was
- Subjects :
- 610 Medicine & health
360 Social problems & social services
3. Good health
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi...........d53ef1b8e1a00e98c9db82f97a395bfe