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ChemInform Abstract: Total Synthesis of NSTX-3, Spider Toxin of Nephila maculata

Authors :
Tateaki Wakamiya
Yoshio Aramaki
Nobufumi Kawai
Tadashi Teshima
Takahiro Matsumoto
Terumi Nakajima
Tetsuo Shiba
Source :
ChemInform. 22
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

A spider toxin NSTX-3 obtained from the venom of Papua New Guinean spider, Nephila maculata was synthesized in order to confirm its proposed structure and to supply the sample for the biological tests. The structure of NSTX-3 is now established as 2,4-dihydroxyphenylacetyl-L-Asn→Cad←Pua←L-Arg, where Cad stands for cadaverine and Pua for putreanine.

Details

ISSN :
09317597
Volume :
22
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........d4ed196c00a7c2959aed5b0b8ea6e90f
Full Text :
https://doi.org/10.1002/chin.199129262