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Phase I study of NGR-hTNF administered at high doses in refractory patients with solid tumors

Authors :
Lorenza Rimassa
Claudio Bordignon
Tiziana Pressiani
Antonio Lambiase
Matteo Simonelli
Maria Chiara Tronconi
Paolo Andrea Zucali
F. De Vincenzo
Antonella Santoro
C. Carnaghi
Source :
Journal of Clinical Oncology. 28:e13091-e13091
Publication Year :
2010
Publisher :
American Society of Clinical Oncology (ASCO), 2010.

Abstract

e13091 Background: NGR-hTNF is a vascular targeting agent exploiting a tumor homing peptide (NGR) that selectively binds an aminopeptidase N overexpressed on tumor blood vessels. Previously, a phas...

Details

ISSN :
15277755 and 0732183X
Volume :
28
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........d4c3a7654da945a5ba95059b9b3f268b