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Impact of single embryo transfer on the overall and twin-pregnancy rates of an IVF/ICSI programme
- Source :
- Reproductive BioMedicine Online. 2:172-177
- Publication Year :
- 2001
- Publisher :
- Elsevier BV, 2001.
-
Abstract
- This retrospective cohort study analyses experience with single embryo transfer (SET) in an lVF/intracytoplasmic sperm injection (ICSI) programme over a 3-year period (1998-2000): 1143 IVF/ICSI cycles were initiated, resulting in 1073 embryo transfers (93.9%). In 810 (75.4%) transfers of two (n = 580; 54%) or more than two (n = 230; 21.4%) embryos, 279 ongoing pregnancies (34.4%) were obtained. In total, there were 263 SET (24.5%): 207 of a single top quality embryo, resulting in 102 conceptions (49.3%) with 71 ongoing implantations (34.3%, one monozygotic twin); and 56 of a single non-top quality embryo, resulting in 16 conceptions (28.6%) with 11 ongoing implantations (19 .6% ). The percentage of transfers of a single top quality embryo gradually increased from 10% (1998) to 19% (1999) to 26% (2000). The total multiple pregnancy rate decreased from 34% (1998), to 32% ( 1999) and 22% (2000), without affecting the overall ongoing pregnancy rate per transfer: 38% in 1998; 29% in 1999; and 34% in 2000. The average number of transferred embryos decreased from 2.26 ( 1998) to 1.86 (2000). Transfer of a single, strictly defined top quality day 3 embryo in twin-prone IVF/ICSI patients reduced the multiple/twin-pregnancy rate but not the overall pregnancy rate.
- Subjects :
- Gynecology
medicine.medical_specialty
business.industry
medicine.medical_treatment
Obstetrics and Gynecology
Monozygotic twin
Retrospective cohort study
Embryo
Single Embryo Transfer
Ivf icsi
Intracytoplasmic sperm injection
Pregnancy rate
Reproductive Medicine
embryonic structures
medicine
business
Twin Pregnancy
Developmental Biology
Subjects
Details
- ISSN :
- 14726483
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Reproductive BioMedicine Online
- Accession number :
- edsair.doi...........d3e58fde68bc120f7e1ad2bc00749740
- Full Text :
- https://doi.org/10.1016/s1472-6483(10)90001-1