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Tin-Mediated Addition of Bromoaceto-Nitrile to Aldimines

Authors :
Peipei Sun
Yongmin Zhang
Source :
Synthetic Communications. 27:3175-3180
Publication Year :
1997
Publisher :
Informa UK Limited, 1997.

Abstract

In the presence of tin powder, the addition of bromoacetonitrile to aldimines gives β-amino nitriles in THF. Chlorotrimethylsilane can accelerate the reaction.

Details

ISSN :
15322432 and 00397911
Volume :
27
Database :
OpenAIRE
Journal :
Synthetic Communications
Accession number :
edsair.doi...........d37686af1fab7163756e002a56fca150
Full Text :
https://doi.org/10.1080/00397919708004176