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ChemInform Abstract: Synthesis of 1,5-Diarylpyrazol-3-propanoic Acids Towards Inhibition of Cyclooxygenase-1/2 Activity and 5-Lipoxygenase-Mediated LTB4 Formation

Authors :
Maria Teresa Nunez
Francisco Ledo
Erden Banoglu
Bilge Çakir
Gretchen Bain
Burcu Caliskan Erguen
Janice Darlington
Luis Labeaga
Source :
ChemInform. 41
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

A variety of 1,5-diarylpyrazol-3-propanoic acid derivatives is synthesized and evaluated as COX-1/2 and 5-LO-mediated LTB4 synthesis inhibitors.

Details

ISSN :
09317597
Volume :
41
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........d2a33b7ca7557141d6780656ef798f99
Full Text :
https://doi.org/10.1002/chin.201051152