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Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation
- Source :
- American Journal of Respiratory Cell and Molecular Biology. 65:500-512
- Publication Year :
- 2021
- Publisher :
- American Thoracic Society, 2021.
-
Abstract
- Ozone (O3) is a prevalent air pollutant causing lung inflammation. Previous studies demonstrate that O3 oxidizes lipids, such as cholesterol, in the airway to produce oxysterols, such as secosterol...
- Subjects :
- 0301 basic medicine
Pulmonary and Respiratory Medicine
Pollutant
Ozone
Lung
Cholesterol
Clinical Biochemistry
NOD-like receptor
Inflammation
Cell Biology
respiratory system
respiratory tract diseases
03 medical and health sciences
chemistry.chemical_compound
030104 developmental biology
0302 clinical medicine
Mediator
medicine.anatomical_structure
030228 respiratory system
chemistry
Cancer research
medicine
lipids (amino acids, peptides, and proteins)
medicine.symptom
Molecular Biology
Subjects
Details
- ISSN :
- 15354989 and 10441549
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- American Journal of Respiratory Cell and Molecular Biology
- Accession number :
- edsair.doi...........d25dd65a10ef2bfcfb50d62e78e8930c
- Full Text :
- https://doi.org/10.1165/rcmb.2021-0032oc