Enzymes from Extreme Thermophilic Bacteria as Special Catalysts: Studies on a β-Galactosidase from Sulfolobus solfataricus

Biotechnological applications of proteins and enzymes are often hampered by their low stability to heat, pH, organic solvents, and proteolysis. With the aid of protein engineering, however, many attempts are being made to improve the operational stability of current commercial enzymes, and, in a more general sense, to establish guidelines for improving the thermostability of proteins and enzymes (Mozhaev et al. 1988).