ChemInform Abstract: Synthesis and Application of Proline Based Organocatalyst for Highly Enantioselective Aldol Reaction by Hydrogen Bonding

Authors :: Prashant B. Thorat
Santosh V. Goswami
Sudhakar R. Bhusare
Bhimrao C. Khade
Source :: ChemInform. 44
Publication Year :: 2013
Publisher :: Wiley, 2013.
Abstract: PTF is found to be the catalyst of choice for the direct asymmetric aldol reaction of cyclohexanone with aromatic aldehydes to yield the adducts with (nearly) complete diastereoselectivity and good enantioselectivity under optimized conditions.

Subjects :: chemistry.chemical_compound
Aldol reaction
Hydrogen bond
Chemistry
Yield (chemistry)
Enantioselective synthesis
Organic chemistry
Cyclohexanone
General Medicine
Proline
Catalysis
Adduct

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