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Down-regulation of ADAMTS13 activity by serine proteases

Authors :
Yoshihiro Fujimura
Source :
Blood. 105:911-912
Publication Year :
2005
Publisher :
American Society of Hematology, 2005.

Abstract

Comment on Crawley et al, page [1085][1] Left unchecked, ADAMTS13 activity may inhibit platelet adhesion at sites of vascular injury under high shear stress. Crawley and colleagues present evidence that the proteolytic cleavage of ADAMTS13 by coagulation proteinases inhibits its ability to cleave

Details

ISSN :
15280020 and 00064971
Volume :
105
Database :
OpenAIRE
Journal :
Blood
Accession number :
edsair.doi...........ce14be219ffbac307065e90b9381fedc
Full Text :
https://doi.org/10.1182/blood-2004-11-4327