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CONSISTENCY OF LDL-C REDUCTION WITH EVOLOCUMAB: AN ANALYSIS FROM FOURIER

Authors :
Thomas Liu
Marc S. Sabatine
Arman Qamar
Anthony C Keech
Julia F Kuder
Sabina A. Murphy
Robert P. Giugliano
Terje R. Pedersen
Scott M. Wasserman
Christopher E. Kurtz
Peter S. Sever
Source :
Journal of the American College of Cardiology. 71:A1727
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

Questions have been raised about interpatient variability in response to PCSK9 inhibitors. FOURIER was a randomized, pbo-controlled trial of the PCSK9i evolocumab, a fully human mAb, in pts w/ ASCVD on a statin. We examined % change in LDL-C at 4 wks. Pts in either arm who did not receive study

Details

ISSN :
07351097
Volume :
71
Database :
OpenAIRE
Journal :
Journal of the American College of Cardiology
Accession number :
edsair.doi...........cdb4a332007c0a5850b3889309181fbd