Two step treatment for giant malignant gastrointestinal stromal tumor: A case report

Summary Objective Giant Malignant gastrointestinal stromal tumor (MGIST) is a very rare disease in China, the morbidity no more than 3%, around 1/100000/year cases have been reported in the world. It has the characteristic of transfer, easy to recur and high rate of resistance. We present a case of MGIST with Two step treatment. Methods A 54 years old male self-discovery has a mass which was located in the upper abdominal. He has abdominal distension after the meal, without vomit, nausea, eructation, acid regurgitation. A computed tomography (CT) and a gastroscope have been performed two days after admission. CT showed a abdominal mass was located in the left side of the abdominal, the size was 23 × 14cm, the boundary between the fundus of stomach was unclear. Gastroscope showed a huge bulge in the fundus of stomach, occupy the fundus of stomach and the upper body of stomach which revealed a diagnosis of MGIST. In this case, we performed interventional therapy, chemotherapy, surgical treatment and prevent recurrence treatment. Results During each months of the following, the size of the malignant gastrointestinal stromal tumor has been reduced. After 6 months of the targeted therapy, we performed the surgical treatment, and the patient has been discharged after 10 days of the surgery. After 3 months and half years of the surgery, there do not have any uncomfortable and having chemotherapy after surgery. Conclusion Two step treatment can been the maximum benefit for the patient which have the MGIST.