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Endosomal recycling reconciles the Alzheimer’s disease paradox

Authors :
Gregory A. Petsko
Scott A. Small
Source :
Science Translational Medicine. 12
Publication Year :
2020
Publisher :
American Association for the Advancement of Science (AAAS), 2020.

Abstract

A hub-and-spoke model with endosomal recycling as the hub can reconcile the pathogenic contribution of amyloid precursor protein to Alzheimer’s disease.

Details

ISSN :
19466242 and 19466234
Volume :
12
Database :
OpenAIRE
Journal :
Science Translational Medicine
Accession number :
edsair.doi...........cc24914aca49da24d2b75ea433c27cf7