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Long-term follow-up on fetuses with isolated sonographic finding of short long bones: a cohort study
- Source :
- Archives of Gynecology and Obstetrics. 301:459-463
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- To evaluate the long-term outcome of fetuses with a diagnosis of isolated short long bones. A retrospective review was conducted of all cases diagnosed with short long bones above 20 weeks of gestation during 2010–2017 in a single tertiary center. Exclusion criteria included abnormal sonographic findings other than short long bones, suspected genetic syndromes, chromosomal abnormalities, and abnormal Doppler flow indices. Follow-up was carried out by telephone questionnaire. During the study period, 54 (24.32%) women met inclusion criteria. Mean gestational age at delivery was 38.05 years (± 2.42 SD). Mean birth weight was 12–19th percentile according to the local fetal growth charts [2645 g (± 684 SD) 95% CI 2173–2980]. Median time for post-natal follow-up was 9.3 years (IQR 6.6–10.75). Growth below the 10th percentile was demonstrated in 27 (50%) children. 11 (20.37%) children were followed up by endocrinological clinics, of them 7 (12.96%) were treated with growth hormone. Three (5.6%) of the children were diagnosed with attention deficit hyperactivity disorder, an incidence that is considered lower than that of the general population (± 9%). Prenatal fetal isolated short long bones diagnosed during the late second and third trimester is associated with short stature. No neurodevelopmental impact was observed in our study group.
- Subjects :
- Short long bone
Percentile
education.field_of_study
Pediatrics
medicine.medical_specialty
030219 obstetrics & reproductive medicine
business.industry
Incidence (epidemiology)
Birth weight
Population
Obstetrics and Gynecology
Gestational age
General Medicine
Short stature
03 medical and health sciences
0302 clinical medicine
030220 oncology & carcinogenesis
Medicine
medicine.symptom
business
education
Cohort study
Subjects
Details
- ISSN :
- 14320711 and 09320067
- Volume :
- 301
- Database :
- OpenAIRE
- Journal :
- Archives of Gynecology and Obstetrics
- Accession number :
- edsair.doi...........cc1a3e2c5f6b1ae3cff9d507e6de3fc0