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New Indole Alkaloids from the Sponge Plakortis sp

Authors :
Kaoru Yamada
Nicole J. de Voogd
Daisuke Uemura
Novriyandi Hanif
Yoshinori Kawazoe
M. Kitamura
Source :
Chemistry of Natural Compounds. 51:1130-1133
Publication Year :
2015
Publisher :
Springer Science and Business Media LLC, 2015.

Abstract

An unprecedented bis-indole 1, a novel indole alkaloid 2, and some known indole-related compounds 3–5 have been isolated from the sponge Plakortis sp. collected from Zampa in Okinawa. Their structures were elucidated by spectroscopic analysis. These metabolites showed cytotoxic activity against P388 leukemia and B16 melanoma cells.

Subjects

Subjects :
Indole test
biology
Indole alkaloid
Stereochemistry
Chemistry
Plant Science
General Chemistry
biology.organism_classification
General Biochemistry, Genetics and Molecular Biology
Sponge
P388 leukemia
Cytotoxicity
Two-dimensional nuclear magnetic resonance spectroscopy
B16 melanoma

Details

ISSN :
15738388 and 00093130
Volume :
51
Database :
OpenAIRE
Journal :
Chemistry of Natural Compounds
Accession number :
edsair.doi...........cbe9de5f7b6d8e32b4016dc445c8da3b
Full Text :
https://doi.org/10.1007/s10600-015-1508-0
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