Low-melting molecular complexes. Part 5. Co-crystals of tetrahydrofuran and diethyl ether with methyl halides

The molecular complexes of tetrahydrofuran (THF) and diethyl ether (DEE) with chloroform (CF), dichlodromethane (DCM) and bromoform (BF) have been synthesised by in situ cryo-crystallization and their structures have been determined by single-crystal X-ray diffraction. CF forms 2:1 co-crystals with THF and DEE, where the components are linked in isolated 2:1 complexes by Cl3 C-H…O interactions. Molecules of components in THF-BF complex form halogen-bonded chains, while the complexes DCM and BF with DEE contain two independent pairs of the components linked by C-H…O contacts. Supramolecular architecture of the molecular complexes is analysed using energy-based topology of intermolecular interactions.